| Date | Home | Away | Result |
|---|---|---|---|
| 4/5/16 1:45 PM | Birmingham City | Brighton and Hove Albion | 1-2 |
| 4/5/16 1:45 PM | Middlesbrough FC | Huddersfield Town | 3-0 |
| 4/5/16 1:45 PM | Sheffield Wednesday | Blackburn Rovers | 2-1 |
| 4/5/16 1:45 PM | Brentford FC | Bolton Wanderers | 3-1 |
| 4/5/16 1:45 PM | Bristol City | Rotherham United | 1-1 |
| 4/5/16 1:45 PM | Milton Keynes Dons FC | Wolverhampton Wanderers | 1-2 |
| 4/5/16 1:45 PM | Burnley FC | Cardiff City | 0-0 |
| 4/5/16 1:45 PM | Ipswich Town | Charlton Athletic | 0-0 |
| 4/5/16 1:45 PM | Leeds United | Queens Park Rangers | 1-1 |
| 4/5/16 1:45 PM | Preston North End | Fulham FC | 1-2 |
| 4/5/16 1:45 PM | Derby County | Hull City A.F.C. | 4-0 |
| 4/5/16 2:00 PM | Reading FC | Nottingham Forest | 2-1 |