| Date | Home | Away | Result |
|---|---|---|---|
| 4/29/22 1:45 PM | Queens Park Rangers | Sheffield United | 1-3 |
| 4/30/22 6:30 AM | Barnsley FC | Preston North End | 1-3 |
| 4/30/22 9:00 AM | Nottingham Forest | Swansea City | 5-1 |
| 4/30/22 9:00 AM | Blackburn Rovers | AFC Bournemouth | 0-3 |
| 4/30/22 9:00 AM | FC Blackpool | Derby County | 0-2 |
| 4/30/22 9:00 AM | Bristol City | Hull City A.F.C. | 5-0 |
| 4/30/22 9:00 AM | Coventry City | Huddersfield Town | 1-2 |
| 4/30/22 9:00 AM | Middlesbrough FC | Stoke City | 3-1 |
| 4/30/22 9:00 AM | Millwall FC | Peterborough United | 3-0 |
| 4/30/22 9:00 AM | Reading FC | West Bromwich Albion | 0-1 |
| 4/30/22 9:00 AM | Cardiff City | Birmingham City | 1-1 |
| 5/2/22 11:15 AM | Fulham FC | Luton Town | 7-0 |