| Date | Home | Away | Result |
|---|---|---|---|
| 3/19/22 7:30 AM | Derby County | Coventry City | 1-1 |
| 3/19/22 7:30 AM | Sheffield United | Barnsley FC | 2-0 |
| 3/19/22 10:00 AM | Swansea City | Birmingham City | 0-0 |
| 3/19/22 10:00 AM | Bristol City | West Bromwich Albion | 2-2 |
| 3/19/22 10:00 AM | Huddersfield Town | AFC Bournemouth | 0-3 |
| 3/19/22 10:00 AM | Hull City A.F.C. | Luton Town | 1-3 |
| 3/19/22 10:00 AM | Reading FC | Blackburn Rovers | 1-0 |
| 3/19/22 10:00 AM | Stoke City | Millwall FC | 2-0 |
| 3/20/22 7:30 AM | Queens Park Rangers | Peterborough United | 1-3 |
| 4/5/22 1:45 PM | Preston North End | FC Blackpool | 1-0 |
| 4/26/22 1:45 PM | Fulham FC | Nottingham Forest | 0-1 |
| 4/27/22 1:45 PM | Middlesbrough FC | Cardiff City | 2-0 |