| Date | Home | Away | Result |
|---|---|---|---|
| 1/28/22 1:45 PM | Huddersfield Town | Stoke City | 1-1 |
| 1/29/22 9:00 AM | Barnsley FC | AFC Bournemouth | 0-1 |
| 1/29/22 9:00 AM | Hull City A.F.C. | Swansea City | 2-0 |
| 1/29/22 9:00 AM | Fulham FC | FC Blackpool | 1-1 |
| 1/29/22 9:00 AM | Luton Town | Blackburn Rovers | 0-0 |
| 1/29/22 9:00 AM | Middlesbrough FC | Coventry City | 1-0 |
| 1/29/22 9:00 AM | Millwall FC | West Bromwich Albion | 2-0 |
| 1/29/22 9:00 AM | Preston North End | Bristol City | 2-2 |
| 1/29/22 9:00 AM | Queens Park Rangers | Reading FC | 4-0 |
| 1/29/22 11:30 AM | Peterborough United | Sheffield United | 0-2 |
| 1/30/22 7:30 AM | Derby County | Birmingham City | 2-2 |
| 1/30/22 10:00 AM | Cardiff City | Nottingham Forest | 2-1 |