| Date | Home | Away | Result |
|---|---|---|---|
| 1/15/22 6:30 AM | Luton Town | AFC Bournemouth | 3-2 |
| 1/15/22 6:30 AM | Cardiff City | Blackburn Rovers | 0-1 |
| 1/15/22 9:00 AM | Derby County | Sheffield United | 2-0 |
| 1/15/22 9:00 AM | Fulham FC | Bristol City | 6-2 |
| 1/15/22 9:00 AM | Middlesbrough FC | Reading FC | 2-1 |
| 1/15/22 9:00 AM | Millwall FC | Nottingham Forest | 0-1 |
| 1/15/22 9:00 AM | Peterborough United | Coventry City | 1-4 |
| 1/15/22 9:00 AM | Preston North End | Birmingham City | 1-1 |
| 1/15/22 9:00 AM | Queens Park Rangers | West Bromwich Albion | 1-0 |
| 1/15/22 9:00 AM | Huddersfield Town | Swansea City | 1-1 |
| 1/16/22 6:00 AM | Hull City A.F.C. | Stoke City | 0-2 |
| 4/26/22 1:45 PM | Barnsley FC | FC Blackpool | 0-2 |