| Date | Home | Away | Result |
|---|---|---|---|
| 12/29/21 1:45 PM | Blackburn Rovers | Barnsley FC | 2-1 |
| 12/29/21 1:45 PM | FC Blackpool | Middlesbrough FC | 1-2 |
| 12/29/21 1:45 PM | Coventry City | Millwall FC | 0-1 |
| 12/30/21 1:45 PM | Stoke City | Derby County | 1-2 |
| 12/30/21 1:45 PM | AFC Bournemouth | Cardiff City | 3-0 |
| 12/30/21 1:45 PM | Bristol City | Queens Park Rangers | 1-2 |
| 12/30/21 1:45 PM | Nottingham Forest | Huddersfield Town | 0-1 |
| 1/11/22 2:00 PM | Reading FC | Fulham FC | 0-7 |
| 1/25/22 1:45 PM | Birmingham City | Peterborough United | 2-2 |
| 1/26/22 2:00 PM | West Bromwich Albion | Preston North End | 0-2 |
| 2/1/22 1:45 PM | Swansea City | Luton Town | 0-1 |
| 2/15/22 1:45 PM | Sheffield United | Hull City A.F.C. | 0-0 |