| Date | Home | Away | Result |
|---|---|---|---|
| 3/12/21 1:45 PM | Blackburn Rovers | Brentford FC | 0-1 |
| 3/13/21 6:15 AM | Luton Town | Swansea City | 0-1 |
| 3/13/21 9:00 AM | Cardiff City | Watford FC | 1-2 |
| 3/13/21 9:00 AM | Wycombe Wanderers | Preston North End | 1-0 |
| 3/13/21 9:00 AM | Middlesbrough FC | Stoke City | 3-0 |
| 3/13/21 9:00 AM | Derby County | Millwall FC | 0-1 |
| 3/13/21 9:00 AM | Nottingham Forest | Reading FC | 1-1 |
| 3/13/21 9:00 AM | Queens Park Rangers | Huddersfield Town | 0-1 |
| 3/13/21 9:00 AM | Birmingham City | Bristol City | 0-3 |
| 3/13/21 9:00 AM | AFC Bournemouth | Barnsley FC | 2-3 |
| 3/14/21 7:15 AM | Sheffield Wednesday | Norwich City | 1-2 |
| 4/15/21 1:00 PM | Rotherham United | Coventry City | 0-1 |