| Date | Home | Away | Result |
|---|---|---|---|
| 3/2/21 1:00 PM | Coventry City | Middlesbrough FC | 1-2 |
| 3/2/21 1:00 PM | Huddersfield Town | Birmingham City | 1-1 |
| 3/2/21 1:00 PM | Millwall FC | Preston North End | 2-1 |
| 3/2/21 1:00 PM | Cardiff City | Derby County | 4-0 |
| 3/2/21 1:45 PM | Nottingham Forest | Luton Town | 0-1 |
| 3/2/21 2:00 PM | Reading FC | Blackburn Rovers | 1-0 |
| 3/3/21 11:30 AM | Norwich City | Brentford FC | 1-0 |
| 3/3/21 1:00 PM | Watford FC | Wycombe Wanderers | 2-0 |
| 3/3/21 1:00 PM | Queens Park Rangers | Barnsley FC | 1-3 |
| 3/3/21 1:45 PM | Bristol City | AFC Bournemouth | 1-2 |
| 3/3/21 1:45 PM | Sheffield Wednesday | Rotherham United | 1-2 |
| 3/3/21 2:15 PM | Stoke City | Swansea City | 1-2 |