| Date | Home | Away | Result |
|---|---|---|---|
| 2/19/21 1:45 PM | Watford FC | Derby County | 2-1 |
| 2/20/21 6:30 AM | Coventry City | Brentford FC | 2-0 |
| 2/20/21 9:00 AM | Sheffield Wednesday | Birmingham City | 0-1 |
| 2/20/21 9:00 AM | Queens Park Rangers | AFC Bournemouth | 2-1 |
| 2/20/21 9:00 AM | Stoke City | Luton Town | 3-0 |
| 2/20/21 9:00 AM | Nottingham Forest | Blackburn Rovers | 1-0 |
| 2/20/21 9:00 AM | Reading FC | Middlesbrough FC | 0-2 |
| 2/20/21 9:00 AM | Bristol City | Barnsley FC | 0-1 |
| 2/20/21 9:00 AM | Cardiff City | Preston North End | 4-0 |
| 2/20/21 9:00 AM | Huddersfield Town | Swansea City | 4-1 |
| 2/20/21 9:00 AM | Norwich City | Rotherham United | 1-0 |
| 2/20/21 9:00 AM | Millwall FC | Wycombe Wanderers | 0-0 |