| Date | Home | Away | Result |
|---|---|---|---|
| 9/25/20 1:45 PM | Huddersfield Town | Nottingham Forest | 1-0 |
| 9/26/20 6:30 AM | Watford FC | Luton Town | 1-0 |
| 9/26/20 6:30 AM | Wycombe Wanderers | Swansea City | 0-2 |
| 9/26/20 9:00 AM | Cardiff City | Reading FC | 1-2 |
| 9/26/20 9:00 AM | Birmingham City | Rotherham United | 1-1 |
| 9/26/20 9:00 AM | Derby County | Blackburn Rovers | 0-4 |
| 9/26/20 9:00 AM | Queens Park Rangers | Middlesbrough FC | 1-1 |
| 9/26/20 9:00 AM | Preston North End | Stoke City | 0-1 |
| 9/26/20 9:00 AM | Millwall FC | Brentford FC | 1-1 |
| 9/26/20 9:00 AM | Barnsley FC | Coventry City | 0-0 |
| 9/27/20 7:00 AM | Bristol City | Sheffield Wednesday | 2-0 |
| 9/27/20 10:00 AM | AFC Bournemouth | Norwich City | 1-0 |