| Date | Home | Away | Result |
|---|---|---|---|
| 12/18/20 2:00 PM | Preston North End | Bristol City | 1-0 |
| 12/19/20 6:30 AM | Norwich City | Cardiff City | 2-0 |
| 12/19/20 9:00 AM | Huddersfield Town | Watford FC | 2-0 |
| 12/19/20 9:00 AM | Swansea City | Barnsley FC | 2-0 |
| 12/19/20 9:00 AM | Sheffield Wednesday | Coventry City | 1-0 |
| 12/19/20 9:00 AM | Wycombe Wanderers | Queens Park Rangers | 1-1 |
| 12/19/20 9:00 AM | Luton Town | AFC Bournemouth | 0-0 |
| 12/19/20 9:00 AM | Brentford FC | Reading FC | 3-1 |
| 12/19/20 9:00 AM | Birmingham City | Middlesbrough FC | 1-4 |
| 12/19/20 9:00 AM | Stoke City | Blackburn Rovers | 1-0 |
| 12/19/20 9:00 AM | Millwall FC | Nottingham Forest | 1-1 |
| 2/3/21 1:00 PM | Rotherham United | Derby County | 3-0 |