| Date | Home | Away | Result |
|---|---|---|---|
| 10/21/17 9:00 AM | Aston Villa | Fulham FC | 2-1 |
| 10/21/17 9:00 AM | Wolverhampton Wanderers | Preston North End | 3-2 |
| 10/21/17 9:00 AM | Middlesbrough FC | Cardiff City | 0-1 |
| 10/21/17 9:00 AM | Bristol City | Leeds United | 0-3 |
| 10/21/17 9:00 AM | Barnsley FC | Hull City A.F.C. | 0-1 |
| 10/21/17 9:00 AM | Sheffield United | Reading FC | 2-1 |
| 10/21/17 9:00 AM | Nottingham Forest | Burton Albion | 2-0 |
| 10/21/17 9:00 AM | Derby County | Sheffield Wednesday | 2-0 |
| 10/21/17 9:00 AM | Bolton Wanderers | Queens Park Rangers | 1-1 |
| 10/21/17 9:00 AM | Brentford FC | AFC Sunderland | 3-3 |
| 10/21/17 11:30 AM | Millwall FC | Birmingham City | 2-0 |
| 10/22/17 6:00 AM | Ipswich Town | Norwich City | 0-1 |