| Date | Home | Away | Result |
|---|---|---|---|
| 10/21/16 1:45 PM | Burton Albion | Birmingham City | 2-0 |
| 10/22/16 9:00 AM | Brentford FC | Barnsley FC | 0-2 |
| 10/22/16 9:00 AM | Rotherham United | Reading FC | 0-1 |
| 10/22/16 9:00 AM | Aston Villa | Fulham FC | 1-0 |
| 10/22/16 9:00 AM | Sheffield Wednesday | Queens Park Rangers | 1-0 |
| 10/22/16 9:00 AM | Wigan Athletic | Brighton and Hove Albion | 0-1 |
| 10/22/16 9:00 AM | Norwich City | Preston North End | 0-1 |
| 10/22/16 9:00 AM | Newcastle United | Ipswich Town | 3-0 |
| 10/22/16 9:00 AM | Bristol City | Blackburn Rovers | 1-0 |
| 10/22/16 9:00 AM | Huddersfield Town | Derby County | 1-0 |
| 10/22/16 9:00 AM | Wolverhampton Wanderers | Leeds United | 0-1 |
| 10/22/16 11:30 AM | Nottingham Forest | Cardiff City | 1-2 |