| Date | Home | Away | Result |
|---|---|---|---|
| 5/1/26 8:00 AM | SSC Bari | Virtus Entella | 2-0 |
| 5/1/26 8:00 AM | Carrarese Calcio 1908 | FC Cesena | 0-0 |
| 5/1/26 8:00 AM | Mantova 1911 | AC Monza | 3-2 |
| 5/1/26 8:00 AM | Modena FC | AC Reggiana 1919 | 2-1 |
| 5/1/26 8:00 AM | FC Empoli | US Avellino | 1-0 |
| 5/1/26 8:00 AM | Juve Stabia | Frosinone Calcio | 0-1 |
| 5/1/26 8:00 AM | Sampdoria Genua | FC Südtirol | 1-0 |
| 5/1/26 8:00 AM | Spezia Calcio | FC Venice | 2-2 |
| 5/1/26 8:00 AM | Padova Calcio | Pescara Calcio | 1-0 |
| 5/1/26 8:00 AM | Palermo FC | US Catanzaro 1929 | 3-2 |