| Date | Home | Away | Result |
|---|---|---|---|
| 12/12/25 1:30 PM | CyD Leonesa | SD Huesca | 0-2 |
| 12/13/25 7:00 AM | Cordoba CF | SD Eibar | 0-0 |
| 12/13/25 9:15 AM | Sporting Gijon | FC Granada | 1-0 |
| 12/13/25 9:15 AM | Real Valladolid | Andorra CF | 0-1 |
| 12/13/25 11:30 AM | Racing Santander | CD Leganes | 1-1 |
| 12/13/25 2:00 PM | Real Saragossa | FC Cadiz | 1-2 |
| 12/13/25 2:00 PM | Deportivo La Coruna | Real Sociedad B | 0-3 |
| 12/14/25 9:15 AM | Albacete Balompie | FC Malaga | --- |
| 12/14/25 11:30 AM | UD Almeria | Burgos CF | --- |
| 12/14/25 2:00 PM | AD Ceuta FC | UD Las Palmas | --- |
| 12/15/25 1:30 PM | CD Castellon | CD Mirandes | --- |