| Date | Home | Away | Result |
|---|---|---|---|
| 12/22/22 7:15 PM | New York Jets | Jacksonville Jaguars | 3-19 |
| 12/24/22 12:00 PM | Chicago Bears | Buffalo Bills | 13-35 |
| 12/24/22 12:00 PM | Minnesota Vikings | New York Giants | 27-24 |
| 12/24/22 12:00 PM | Carolina Panthers | Detroit Lions | 37-23 |
| 12/24/22 12:00 PM | Baltimore Ravens | Atlanta Falcons | 17-9 |
| 12/24/22 12:00 PM | New England Patriots | Cincinnati Bengals | 18-22 |
| 12/24/22 12:00 PM | Cleveland Browns | New Orleans Saints | 10-17 |
| 12/24/22 12:00 PM | Kansas City Chiefs | Seattle Seahawks | 24-10 |
| 12/24/22 1:02 PM | Tennessee Titans | Houston Texans | 14-19 |
| 12/24/22 3:05 PM | San Francisco 49ers | Washington Commanders | 37-20 |
| 12/24/22 3:25 PM | Dallas Cowboys | Philadelphia Eagles | 40-34 |
| 12/24/22 7:15 PM | Pittsburgh Steelers | Las Vegas Raiders | 13-10 |
| 12/25/22 12:00 PM | Miami Dolphins | Green Bay Packers | 20-26 |
| 12/25/22 3:30 PM | Los Angeles Rams | Denver Broncos | 51-14 |
| 12/25/22 7:20 PM | Arizona Cardinals | Tampa Bay Buccaneers | 16-19OT |
| 12/26/22 7:15 PM | Indianapolis Colts | Los Angeles Chargers | 3-20 |