| Date | Home | Away | Result |
|---|---|---|---|
| 11/10/22 7:15 PM | Carolina Panthers | Atlanta Falcons | 25-15 |
| 11/13/22 8:30 AM | Tampa Bay Buccaneers | Seattle Seahawks | 21-16 |
| 11/13/22 12:00 PM | Kansas City Chiefs | Jacksonville Jaguars | 27-17 |
| 11/13/22 12:00 PM | Chicago Bears | Detroit Lions | 30-31 |
| 11/13/22 12:00 PM | Pittsburgh Steelers | New Orleans Saints | 20-10 |
| 11/13/22 12:00 PM | Miami Dolphins | Cleveland Browns | 39-17 |
| 11/13/22 12:00 PM | Tennessee Titans | Denver Broncos | 17-10 |
| 11/13/22 12:00 PM | New York Giants | Houston Texans | 24-16 |
| 11/13/22 12:00 PM | Buffalo Bills | Minnesota Vikings | 30-33OT |
| 11/13/22 3:05 PM | Las Vegas Raiders | Indianapolis Colts | 20-25 |
| 11/13/22 3:25 PM | Green Bay Packers | Dallas Cowboys | 31-28OT |
| 11/13/22 3:25 PM | Los Angeles Rams | Arizona Cardinals | 17-27 |
| 11/13/22 7:20 PM | San Francisco 49ers | Los Angeles Chargers | 22-16 |
| 11/14/22 7:15 PM | Philadelphia Eagles | Washington Commanders | 21-32 |