| Date | Home | Away | Group | Result |
|---|---|---|---|---|
| 4/23/24 5:00 PM | Caracas FC | Rosario Central | Group G | 1-1 |
| 4/23/24 5:00 PM | Estudiantes de La Plata | Gremio Porto Alegre | Group C | 0-1 |
| 4/23/24 7:00 PM | Club Atletico Mineiro | Club Atlético Peñarol | Group G | 3-2 |
| 4/23/24 7:00 PM | Liverpool F.C. | CA San Lorenzo | Group F | 1-0 |
| 4/23/24 7:30 PM | Colo-Colo | Alianza Lima | Group A | 0-0 |
| 4/23/24 9:00 PM | Junior FC | LDU Quito | Group D | 1-1 |
| 4/24/24 5:00 PM | Club Nacional de Football | Deportivo Tachira | Group H | 2-1 |
| 4/24/24 5:00 PM | Botafogo | Universitario | Group D | 3-1 |
| 4/24/24 5:00 PM | Huachipato | The Strongest | Group C | 0-0 |
| 4/24/24 7:30 PM | Club Libertad | River Plate | Group H | 1-2 |
| 4/24/24 7:30 PM | Independiente del Valle | Palmeiras | Group F | 2-3 |
| 4/24/24 7:30 PM | Club Bolívar | Flamengo | Group E | 2-1 |
| 4/25/24 5:00 PM | Cobresal | CA Talleres | Group B | 0-2 |
| 4/25/24 5:00 PM | Club Cerro Porteno | Fluminense | Group A | 0-0 |
| 4/25/24 7:00 PM | Palestino | Millonarios FC | Group E | 3-1 |
| 4/25/24 7:00 PM | Barcelona SC | FC Sao Paulo | Group B | 0-2 |