| Date | Home | Away | Group | Result |
|---|---|---|---|---|
| 4/2/24 5:00 PM | Millonarios FC | Flamengo | Group E | 1-1 |
| 4/2/24 5:00 PM | Cobresal | Barcelona SC | Group B | 1-1 |
| 4/2/24 7:00 PM | The Strongest | Gremio Porto Alegre | Group C | 2-0 |
| 4/2/24 7:30 PM | Deportivo Tachira | River Plate | Group H | 0-2 |
| 4/2/24 9:00 PM | Universitario | LDU Quito | Group D | 2-1 |
| 4/3/24 5:00 PM | Club Nacional de Football | Club Libertad | Group H | 2-0 |
| 4/3/24 5:00 PM | Botafogo | Junior FC | Group D | 1-3 |
| 4/3/24 5:00 PM | Huachipato | Estudiantes de La Plata | Group C | 1-1 |
| 4/3/24 7:00 PM | Colo-Colo | Club Cerro Porteno | Group A | 1-0 |
| 4/3/24 7:30 PM | CA San Lorenzo | Palmeiras | Group F | 1-1 |
| 4/3/24 7:30 PM | Alianza Lima | Fluminense | Group A | 1-1 |
| 4/4/24 5:00 PM | Rosario Central | Club Atlético Peñarol | Group G | 1-0 |
| 4/4/24 5:00 PM | Caracas FC | Club Atletico Mineiro | Group G | 1-4 |
| 4/4/24 7:00 PM | Liverpool F.C. | Independiente del Valle | Group F | 1-1 |
| 4/4/24 7:00 PM | Palestino | Club Bolívar | Group E | 0-4 |
| 4/4/24 7:00 PM | CA Talleres | FC Sao Paulo | Group B | 2-1 |