| Date | Home | Away | Result |
|---|---|---|---|
| 12/11/25 11:45 AM | Fiorentina | Dynamo Kiew | --- |
| 12/11/25 11:45 AM | Jagiellonia Bialystok | Rayo Vallecano | --- |
| 12/11/25 11:45 AM | KF Drita Gjilan | AZ Alkmaar | --- |
| 12/11/25 11:45 AM | Breidablik Kopavogur | Shamrock Rovers | --- |
| 12/11/25 11:45 AM | Samsunspor | AEK Athens | --- |
| 12/11/25 11:45 AM | KF Shkendija | SK Slovan Bratislava | --- |
| 12/11/25 11:45 AM | BK Häcken | AEK Larnaka | --- |
| 12/11/25 11:45 AM | Universitatea Craiova | Sparta Prag | --- |
| 12/11/25 11:45 AM | FC Noah | Legia Warschau | --- |
| 12/11/25 2:00 PM | SK Rapid Wien | Omonia Nicosia | --- |
| 12/11/25 2:00 PM | Lech Poznan | FSV Mainz 05 | --- |
| 12/11/25 2:00 PM | HNK Rijeka | NK Celje | --- |
| 12/11/25 2:00 PM | Lincoln Red Imps FC | Sigma Olomouc | --- |
| 12/11/25 2:00 PM | Kuopion PS | FC Lausanne-Sport | --- |
| 12/11/25 2:00 PM | FC Aberdeen | Racing Club Strasbourg | --- |
| 12/11/25 2:00 PM | KS Rakow Czestochowa | HŠK Zrinjski Mostar | --- |
| 12/11/25 2:00 PM | Hamrun Spartans | Schachtjor Donezk | --- |
| 12/11/25 2:00 PM | FC Shelbourne | Crystal Palace | --- |