Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 5/14/22 8:30 AM | 5/14/22 8:00 AM | VfB Stuttgart | 1. FC Köln | 2-1 | 1 - 3 points |
| 5/14/22 8:30 AM | 5/14/22 8:00 AM | Bor. Mönchengladbach | 1899 Hoffenheim | 5-1 | 1 - 3 points |
| 5/14/22 8:30 AM | 5/14/22 8:00 AM | 1. FC Union Berlin | VfL Bochum | 3-2 | 1 - 3 points |
| 5/14/22 8:30 AM | 5/14/22 8:00 AM | Bayer 04 Leverkusen | SC Freiburg | 2-1 | 1 - 3 points |
| 5/14/22 8:30 AM | 5/14/22 8:00 AM | Borussia Dortmund | Hertha BSC | 2-1 | 1 - 3 points |
| 5/14/22 8:30 AM | 5/14/22 8:00 AM | Arminia Bielefeld | RB Leipzig | 1-1 | 1 - 3 points |
| 5/14/22 8:30 AM | 5/14/22 8:00 AM | FC Augsburg | SpVgg Greuther Fürth | 2-1 | 1 - 3 points |
| 5/14/22 8:30 AM | 5/14/22 8:00 AM | FSV Mainz 05 | Eintracht Frankfurt | 2-2 | 1 - 3 points |
| 5/14/22 8:35 AM | 5/14/22 8:05 AM | VfL Wolfsburg | FC Bayern Munich | 2-2 | 1 - 3 points |