Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 9/17/21 12:00 PM | 9/17/21 11:59 AM | TSV Havelse | FC Viktoria Köln | 1-0 | 2 - 6 points |
| 9/18/21 7:00 AM | 9/18/21 6:59 AM | MSV Duisburg | Eintracht Braunschweig | 3-2 | 2 - 6 points |
| 9/18/21 7:00 AM | 9/18/21 6:59 AM | 1. FC Magdeburg | FC Würzburger Kickers | 1-2 | 2 - 6 points |
| 9/18/21 7:00 AM | 9/18/21 6:59 AM | 1. FC Saarbrücken | Türkgücü München | 3-1 | 2 - 6 points |
| 9/18/21 7:00 AM | 9/18/21 6:59 AM | TSV 1860 Munich | FSV Zwickau | 0-2 | 2 - 6 points |
| 9/18/21 7:00 AM | 9/18/21 6:59 AM | SV Waldhof Mannheim | Hallescher FC | 2-1 | 2 - 6 points |
| 9/18/21 7:00 AM | 9/18/21 6:59 AM | VfL Osnabrück | SV Meppen | 1-0 | 2 - 6 points |
| 9/19/21 6:00 AM | 9/19/21 5:59 AM | SC Freiburg II | Viktoria 1889 Berlin | 2-0 | 2 - 6 points |
| 9/19/21 7:00 AM | 9/19/21 6:59 AM | SC Verl | 1. FC Kaiserslautern | 0-2 | 2 - 6 points |
| 9/20/21 12:00 PM | 9/20/21 11:59 AM | SV Wehen Wiesbaden | Borussia Dortmund II | 0-1 | 2 - 6 points |