Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 9/3/21 12:00 PM | 9/3/21 11:59 AM | 1. FC Saarbrücken | SV Wehen Wiesbaden | 3-4 | 2 - 6 points |
| 9/4/21 7:00 AM | 9/4/21 6:59 AM | SC Verl | Viktoria 1889 Berlin | 3-3 | 2 - 6 points |
| 9/4/21 7:00 AM | 9/4/21 6:59 AM | SV Waldhof Mannheim | Türkgücü München | 3-0 | 2 - 6 points |
| 9/4/21 7:00 AM | 9/4/21 6:59 AM | MSV Duisburg | FC Würzburger Kickers | 2-0 | 2 - 6 points |
| 9/4/21 7:00 AM | 9/4/21 6:59 AM | TSV 1860 Munich | SV Meppen | 1-1 | 2 - 6 points |
| 9/4/21 11:00 AM | 9/4/21 10:59 AM | 1. FC Magdeburg | 1. FC Kaiserslautern | 1-0 | 2 - 6 points |
| 9/5/21 7:00 AM | 9/5/21 6:59 AM | TSV Havelse | Borussia Dortmund II | 0-1 | 2 - 6 points |
| 9/6/21 12:00 PM | 9/6/21 11:59 AM | VfL Osnabrück | FC Viktoria Köln | 3-0 | 2 - 6 points |
| 9/15/21 12:00 PM | 9/15/21 11:59 AM | FSV Zwickau | Hallescher FC | 2-2 | 2 - 6 points |
| 9/22/21 12:00 PM | 9/22/21 11:59 AM | SC Freiburg II | Eintracht Braunschweig | 0-1 | 2 - 6 points |