Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 8/24/21 12:00 PM | 8/24/21 11:59 AM | Hallescher FC | 1. FC Kaiserslautern | 1-0 | 2 - 6 points |
| 8/24/21 12:00 PM | 8/24/21 11:59 AM | TSV 1860 Munich | FC Viktoria Köln | 3-0 | 2 - 6 points |
| 8/24/21 12:00 PM | 8/24/21 11:59 AM | SV Waldhof Mannheim | SV Meppen | 5-0 | 2 - 6 points |
| 8/24/21 12:00 PM | 8/24/21 11:59 AM | FSV Zwickau | Viktoria 1889 Berlin | 1-1 | 2 - 6 points |
| 8/24/21 12:00 PM | 8/24/21 11:59 AM | SC Verl | Eintracht Braunschweig | 0-3 | 2 - 6 points |
| 8/25/21 12:00 PM | 8/25/21 11:59 AM | VfL Osnabrück | Borussia Dortmund II | 2-1 | 2 - 6 points |
| 8/25/21 12:00 PM | 8/25/21 11:59 AM | SC Freiburg II | FC Würzburger Kickers | 1-0 | 2 - 6 points |
| 8/25/21 12:00 PM | 8/25/21 11:59 AM | MSV Duisburg | SV Wehen Wiesbaden | 0-2 | 2 - 6 points |
| 8/25/21 12:00 PM | 8/25/21 11:59 AM | TSV Havelse | Türkgücü München | 0-3 | 2 - 6 points |
| 8/25/21 12:00 PM | 8/25/21 11:59 AM | 1. FC Saarbrücken | 1. FC Magdeburg | 2-1 | 2 - 6 points |