Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 4/1/22 12:00 PM | 4/1/22 11:59 AM | SV Meppen | SV Wehen Wiesbaden | 0-4 | 2 - 6 points |
| 4/2/22 7:00 AM | 4/2/22 6:59 AM | FC Viktoria Köln | Borussia Dortmund II | 0-2 | 2 - 6 points |
| 4/2/22 7:00 AM | 4/2/22 6:59 AM | SC Verl | SC Freiburg II | 3-1 | 2 - 6 points |
| 4/2/22 7:00 AM | 4/2/22 6:59 AM | 1. FC Kaiserslautern | MSV Duisburg | 5-1 | 2 - 6 points |
| 4/2/22 7:00 AM | 4/2/22 6:59 AM | Eintracht Braunschweig | TSV Havelse | 3-2 | 2 - 6 points |
| 4/2/22 7:00 AM | 4/2/22 6:59 AM | TSV 1860 Munich | 1. FC Saarbrücken | 1-1 | 2 - 6 points |
| 4/3/22 6:00 AM | 4/3/22 5:59 AM | FSV Zwickau | SV Waldhof Mannheim | 1-1 | 2 - 6 points |
| 4/4/22 12:00 PM | 4/4/22 11:59 AM | Viktoria 1889 Berlin | 1. FC Magdeburg | 2-1 | 2 - 6 points |
| 4/19/22 12:00 PM | 4/19/22 11:59 AM | Hallescher FC | VfL Osnabrück | 3-3 | 2 - 6 points |