Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 3/18/22 1:00 PM | 3/18/22 12:59 PM | FC Würzburger Kickers | FC Viktoria Köln | 0-1 | 2 - 6 points |
| 3/19/22 8:00 AM | 3/19/22 7:59 AM | 1. FC Saarbrücken | Hallescher FC | 2-1 | 2 - 6 points |
| 3/19/22 8:00 AM | 3/19/22 7:59 AM | SC Freiburg II | 1. FC Kaiserslautern | 0-0 | 2 - 6 points |
| 3/19/22 8:00 AM | 3/19/22 7:59 AM | 1. FC Magdeburg | SV Meppen | 0-0 | 2 - 6 points |
| 3/19/22 8:00 AM | 3/19/22 7:59 AM | TSV Havelse | SC Verl | 1-3 | 2 - 6 points |
| 3/19/22 8:00 AM | 3/19/22 7:59 AM | SV Wehen Wiesbaden | Türkgücü München | 1-0 | 2 - 6 points |
| 3/19/22 8:00 AM | 3/19/22 7:59 AM | VfL Osnabrück | Viktoria 1889 Berlin | 3-1 | 2 - 6 points |
| 3/20/22 7:00 AM | 3/20/22 6:59 AM | MSV Duisburg | FSV Zwickau | 0-1 | 2 - 6 points |
| 3/20/22 8:00 AM | 3/20/22 7:59 AM | SV Waldhof Mannheim | TSV 1860 Munich | 3-0 | 2 - 6 points |
| 3/21/22 1:00 PM | 3/21/22 12:59 PM | Borussia Dortmund II | Eintracht Braunschweig | 0-1 | 2 - 6 points |