Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 2/25/22 12:00 PM | 2/25/22 11:59 AM | FC Viktoria Köln | TSV Havelse | 0-0 | 2 - 6 points |
| 2/26/22 7:00 AM | 2/26/22 6:59 AM | FC Würzburger Kickers | 1. FC Magdeburg | 2-4 | 2 - 6 points |
| 2/26/22 7:00 AM | 2/26/22 6:59 AM | Eintracht Braunschweig | MSV Duisburg | 2-1 | 2 - 6 points |
| 2/26/22 7:00 AM | 2/26/22 6:59 AM | Hallescher FC | SV Waldhof Mannheim | 1-2 | 2 - 6 points |
| 2/26/22 7:00 AM | 2/26/22 6:59 AM | FSV Zwickau | TSV 1860 Munich | 1-3 | 2 - 6 points |
| 2/26/22 7:00 AM | 2/26/22 6:59 AM | SV Meppen | VfL Osnabrück | 0-1 | 2 - 6 points |
| 2/26/22 7:00 AM | 2/26/22 6:59 AM | 1. FC Kaiserslautern | SC Verl | 2-1 | 2 - 6 points |
| 2/27/22 6:00 AM | 2/27/22 5:59 AM | Viktoria 1889 Berlin | SC Freiburg II | 0-2 | 2 - 6 points |
| 2/27/22 7:00 AM | 2/27/22 6:59 AM | Borussia Dortmund II | SV Wehen Wiesbaden | 2-3 | 2 - 6 points |
| 2/28/22 12:00 PM | 2/28/22 11:59 AM | Türkgücü München | 1. FC Saarbrücken | 1-5 | 2 - 6 points |