Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 2/19/22 7:00 AM | 2/19/22 6:59 AM | SV Wehen Wiesbaden | Viktoria 1889 Berlin | 2-0 | 2 - 6 points |
| 2/19/22 7:00 AM | 2/19/22 6:59 AM | MSV Duisburg | Türkgücü München | 2-0 | 2 - 6 points |
| 2/19/22 7:00 AM | 2/19/22 6:59 AM | SC Freiburg II | SV Meppen | 2-0 | 2 - 6 points |
| 2/19/22 7:00 AM | 2/19/22 6:59 AM | 1. FC Saarbrücken | FC Viktoria Köln | 0-1 | 2 - 6 points |
| 2/19/22 7:00 AM | 2/19/22 6:59 AM | 1. FC Magdeburg | Borussia Dortmund II | 2-0 | 2 - 6 points |
| 2/20/22 6:00 AM | 2/20/22 5:59 AM | TSV Havelse | FC Würzburger Kickers | 1-3 | 2 - 6 points |
| 2/20/22 7:00 AM | 2/20/22 6:59 AM | SV Waldhof Mannheim | 1. FC Kaiserslautern | 0-0 | 2 - 6 points |
| 2/21/22 12:00 PM | 2/21/22 11:59 AM | TSV 1860 Munich | Hallescher FC | 0-2 | 2 - 6 points |
| 3/26/22 8:00 AM | 3/26/22 7:59 AM | VfL Osnabrück | Eintracht Braunschweig | 1-1 | 2 - 6 points |
| 3/29/22 12:00 PM | 3/29/22 11:59 AM | SC Verl | FSV Zwickau | 0-0 | 2 - 6 points |