Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 2/4/22 12:00 PM | 2/4/22 11:59 AM | SC Freiburg II | FC Viktoria Köln | 1-1 | 2 - 6 points |
| 2/5/22 7:00 AM | 2/5/22 6:59 AM | TSV Havelse | SV Meppen | 3-0 | 2 - 6 points |
| 2/5/22 7:00 AM | 2/5/22 6:59 AM | 1. FC Magdeburg | SV Wehen Wiesbaden | 3-1 | 2 - 6 points |
| 2/5/22 7:00 AM | 2/5/22 6:59 AM | SV Waldhof Mannheim | Viktoria 1889 Berlin | 3-2 | 2 - 6 points |
| 2/5/22 7:00 AM | 2/5/22 6:59 AM | FSV Zwickau | 1. FC Kaiserslautern | 0-2 | 2 - 6 points |
| 2/5/22 7:00 AM | 2/5/22 6:59 AM | SC Verl | Hallescher FC | 0-0 | 2 - 6 points |
| 2/5/22 7:00 AM | 2/5/22 6:59 AM | VfL Osnabrück | Türkgücü München | 1-1 | 2 - 6 points |
| 2/6/22 6:00 AM | 2/6/22 5:59 AM | TSV 1860 Munich | Eintracht Braunschweig | 2-2 | 2 - 6 points |
| 2/6/22 7:00 AM | 2/6/22 6:59 AM | MSV Duisburg | Borussia Dortmund II | 1-3 | 2 - 6 points |
| 2/7/22 12:00 PM | 2/7/22 11:59 AM | 1. FC Saarbrücken | FC Würzburger Kickers | 2-1 | 2 - 6 points |