Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 10/22/21 12:00 PM | 10/22/21 11:59 AM | VfL Osnabrück | Hallescher FC | 0-0 | 2 - 6 points |
| 10/23/21 7:00 AM | 10/23/21 6:59 AM | SV Waldhof Mannheim | FSV Zwickau | 1-1 | 2 - 6 points |
| 10/23/21 7:00 AM | 10/23/21 6:59 AM | 1. FC Magdeburg | Viktoria 1889 Berlin | 1-0 | 2 - 6 points |
| 10/23/21 7:00 AM | 10/23/21 6:59 AM | SV Wehen Wiesbaden | SV Meppen | 3-4 | 2 - 6 points |
| 10/23/21 7:00 AM | 10/23/21 6:59 AM | FC Würzburger Kickers | Türkgücü München | 2-1 | 2 - 6 points |
| 10/23/21 7:00 AM | 10/23/21 6:59 AM | 1. FC Saarbrücken | TSV 1860 Munich | 1-1 | 2 - 6 points |
| 10/23/21 7:00 AM | 10/23/21 6:59 AM | SC Freiburg II | SC Verl | 3-2 | 2 - 6 points |
| 10/24/21 6:00 AM | 10/24/21 5:59 AM | Borussia Dortmund II | FC Viktoria Köln | 0-1 | 2 - 6 points |
| 10/24/21 7:00 AM | 10/24/21 6:59 AM | TSV Havelse | Eintracht Braunschweig | 0-4 | 2 - 6 points |
| 10/25/21 12:00 PM | 10/25/21 11:59 AM | MSV Duisburg | 1. FC Kaiserslautern | 1-1 | 2 - 6 points |