Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 10/15/21 12:00 PM | 10/15/21 11:59 AM | Viktoria 1889 Berlin | VfL Osnabrück | 1-2 | 2 - 6 points |
| 10/16/21 7:00 AM | 10/16/21 6:59 AM | 1. FC Kaiserslautern | SC Freiburg II | 3-0 | 2 - 6 points |
| 10/16/21 7:00 AM | 10/16/21 6:59 AM | FSV Zwickau | MSV Duisburg | 3-2 | 2 - 6 points |
| 10/16/21 7:00 AM | 10/16/21 6:59 AM | SV Meppen | 1. FC Magdeburg | 2-3 | 2 - 6 points |
| 10/16/21 7:00 AM | 10/16/21 6:59 AM | Hallescher FC | 1. FC Saarbrücken | 2-3 | 2 - 6 points |
| 10/16/21 7:00 AM | 10/16/21 6:59 AM | Eintracht Braunschweig | Borussia Dortmund II | 4-2 | 2 - 6 points |
| 10/17/21 6:00 AM | 10/17/21 5:59 AM | Türkgücü München | SV Wehen Wiesbaden | 1-0 | 2 - 6 points |
| 10/17/21 7:00 AM | 10/17/21 6:59 AM | FC Viktoria Köln | FC Würzburger Kickers | 1-1 | 2 - 6 points |
| 10/18/21 12:00 PM | 10/18/21 11:59 AM | SC Verl | TSV Havelse | 5-3 | 2 - 6 points |
| 11/30/21 12:00 PM | 11/30/21 11:59 AM | TSV 1860 Munich | SV Waldhof Mannheim | 1-3 | 2 - 6 points |