Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 10/1/21 12:00 PM | 10/1/21 11:59 AM | 1. FC Saarbrücken | Eintracht Braunschweig | 2-2 | 2 - 6 points |
| 10/2/21 7:00 AM | 10/2/21 6:59 AM | TSV Havelse | 1. FC Kaiserslautern | 0-6 | 2 - 6 points |
| 10/2/21 7:00 AM | 10/2/21 6:59 AM | VfL Osnabrück | FSV Zwickau | 0-1 | 2 - 6 points |
| 10/2/21 7:00 AM | 10/2/21 6:59 AM | SC Freiburg II | Hallescher FC | 1-1 | 2 - 6 points |
| 10/2/21 7:00 AM | 10/2/21 6:59 AM | MSV Duisburg | SV Meppen | 0-1 | 2 - 6 points |
| 10/2/21 7:00 AM | 10/2/21 6:59 AM | TSV 1860 Munich | Viktoria 1889 Berlin | 1-1 | 2 - 6 points |
| 10/2/21 7:00 AM | 10/2/21 6:59 AM | SV Wehen Wiesbaden | FC Viktoria Köln | 1-1 | 2 - 6 points |
| 10/3/21 6:00 AM | 10/3/21 5:59 AM | Borussia Dortmund II | FC Würzburger Kickers | 2-0 | 2 - 6 points |
| 10/3/21 7:00 AM | 10/3/21 6:59 AM | SV Waldhof Mannheim | SC Verl | 2-1 | 2 - 6 points |
| 10/4/21 12:00 PM | 10/4/21 11:59 AM | 1. FC Magdeburg | Türkgücü München | 4-0 | 2 - 6 points |