Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 8/27/21 11:30 AM | 8/27/21 11:30 AM | SV Sandhausen | FC Ingolstadt | 0-2 | 2 - 4 points |
| 8/27/21 11:30 AM | 8/27/21 11:30 AM | 1. FC Nürnberg | Karlsruher SC | 2-1 | 2 - 4 points |
| 8/28/21 6:30 AM | 8/28/21 6:30 AM | Holstein Kiel | Erzgebirge Aue | 3-0 | 2 - 4 points |
| 8/28/21 6:30 AM | 8/28/21 6:30 AM | SV Darmstadt 98 | Hannover 96 | 4-0 | 2 - 4 points |
| 8/28/21 6:30 AM | 8/28/21 6:30 AM | 1. FC Heidenheim 1846 | Hamburger SV | 0-0 | 2 - 4 points |
| 8/28/21 1:30 PM | 8/28/21 1:30 PM | FC Schalke 04 | Fortuna Düsseldorf | 3-1 | 2 - 4 points |
| 8/29/21 6:30 AM | 8/29/21 6:30 AM | Dynamo Dresden | SC Paderborn 07 | 0-3 | 2 - 4 points |
| 8/29/21 6:30 AM | 8/29/21 6:30 AM | Werder Bremen | FC Hansa Rostock | 3-0 | 2 - 4 points |
| 8/29/21 6:30 AM | 8/29/21 6:30 AM | FC St. Pauli | Jahn Regensburg | 2-0 | 2 - 4 points |