Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 3/18/22 12:30 PM | 3/18/22 12:30 PM | FC St. Pauli | 1. FC Heidenheim 1846 | 1-0 | 2 - 4 points |
| 3/18/22 12:30 PM | 3/18/22 12:30 PM | Erzgebirge Aue | Karlsruher SC | 0-3 | 2 - 4 points |
| 3/19/22 7:30 AM | 3/19/22 7:30 AM | FC Schalke 04 | Hannover 96 | 2-1 | 2 - 4 points |
| 3/19/22 7:30 AM | 3/19/22 7:30 AM | Fortuna Düsseldorf | Hamburger SV | 1-1 | 2 - 4 points |
| 3/19/22 7:30 AM | 3/19/22 7:30 AM | SV Sandhausen | FC Hansa Rostock | 0-1 | 2 - 4 points |
| 3/19/22 2:30 PM | 3/19/22 2:30 PM | Werder Bremen | SV Darmstadt 98 | 1-0 | 2 - 4 points |
| 3/20/22 7:30 AM | 3/20/22 7:30 AM | Holstein Kiel | FC Ingolstadt | 1-0 | 2 - 4 points |
| 3/20/22 7:30 AM | 3/20/22 7:30 AM | 1. FC Nürnberg | Dynamo Dresden | 1-1 | 2 - 4 points |
| 3/20/22 7:30 AM | 3/20/22 7:30 AM | Jahn Regensburg | SC Paderborn 07 | 1-0 | 2 - 4 points |