Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 3/11/22 11:30 AM | 3/11/22 11:30 AM | SV Darmstadt 98 | SV Sandhausen | 1-1 | 2 - 4 points |
| 3/11/22 11:30 AM | 3/11/22 11:30 AM | FC Hansa Rostock | Holstein Kiel | 3-2 | 2 - 4 points |
| 3/12/22 6:30 AM | 3/12/22 6:30 AM | SC Paderborn 07 | Fortuna Düsseldorf | 1-1 | 2 - 4 points |
| 3/12/22 6:30 AM | 3/12/22 6:30 AM | Dynamo Dresden | FC St. Pauli | 1-1 | 2 - 4 points |
| 3/12/22 1:30 PM | 3/12/22 1:30 PM | 1. FC Heidenheim 1846 | Werder Bremen | 2-1 | 2 - 4 points |
| 3/13/22 7:30 AM | 3/13/22 7:30 AM | Karlsruher SC | Jahn Regensburg | 1-1 | 2 - 4 points |
| 3/13/22 7:30 AM | 3/13/22 7:30 AM | Hannover 96 | 1. FC Nürnberg | 0-3 | 2 - 4 points |
| 3/13/22 7:30 AM | 3/13/22 7:30 AM | FC Ingolstadt | FC Schalke 04 | 0-3 | 2 - 4 points |
| 4/5/22 11:30 AM | 4/5/22 11:30 AM | Hamburger SV | Erzgebirge Aue | 4-0 | 2 - 4 points |