Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 3/4/22 11:30 AM | 3/4/22 11:30 AM | SV Darmstadt 98 | 1. FC Heidenheim 1846 | 3-2 | 2 - 4 points |
| 3/4/22 11:30 AM | 3/4/22 11:30 AM | Holstein Kiel | SC Paderborn 07 | 3-4 | 2 - 4 points |
| 3/5/22 6:30 AM | 3/5/22 6:30 AM | FC St. Pauli | Karlsruher SC | 3-1 | 2 - 4 points |
| 3/5/22 6:30 AM | 3/5/22 6:30 AM | SV Sandhausen | Hannover 96 | 3-1 | 2 - 4 points |
| 3/5/22 6:30 AM | 3/5/22 6:30 AM | FC Schalke 04 | FC Hansa Rostock | 3-4 | 2 - 4 points |
| 3/5/22 1:30 PM | 3/5/22 1:30 PM | 1. FC Nürnberg | Hamburger SV | 2-1 | 2 - 4 points |
| 3/6/22 6:30 AM | 3/6/22 6:30 AM | Erzgebirge Aue | Jahn Regensburg | 1-0 | 2 - 4 points |
| 3/6/22 6:30 AM | 3/6/22 6:30 AM | Werder Bremen | Dynamo Dresden | 2-1 | 2 - 4 points |
| 3/6/22 6:30 AM | 3/6/22 6:30 AM | Fortuna Düsseldorf | FC Ingolstadt | 3-0 | 2 - 4 points |