Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 1/21/22 11:30 AM | 1/21/22 11:30 AM | Hamburger SV | FC St. Pauli | 2-1 | 2 - 4 points |
| 1/21/22 11:30 AM | 1/21/22 11:30 AM | Fortuna Düsseldorf | 1. FC Nürnberg | 0-1 | 2 - 4 points |
| 1/22/22 6:30 AM | 1/22/22 6:30 AM | FC Ingolstadt | SV Darmstadt 98 | 0-2 | 2 - 4 points |
| 1/22/22 6:30 AM | 1/22/22 6:30 AM | SC Paderborn 07 | Werder Bremen | 3-4 | 2 - 4 points |
| 1/22/22 6:30 AM | 1/22/22 6:30 AM | FC Hansa Rostock | 1. FC Heidenheim 1846 | 0-0 | 2 - 4 points |
| 1/22/22 1:30 PM | 1/22/22 1:30 PM | Erzgebirge Aue | FC Schalke 04 | 0-5 | 2 - 4 points |
| 1/23/22 6:30 AM | 1/23/22 6:30 AM | Hannover 96 | Dynamo Dresden | 0-0 | 2 - 4 points |
| 1/23/22 6:30 AM | 1/23/22 6:30 AM | Jahn Regensburg | Holstein Kiel | 1-2 | 2 - 4 points |
| 2/8/22 11:30 AM | 2/8/22 11:30 AM | Karlsruher SC | SV Sandhausen | 0-2 | 2 - 4 points |