Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 12/3/21 11:30 AM | 12/3/21 11:30 AM | Werder Bremen | Erzgebirge Aue | 4-0 | 2 - 4 points |
| 12/3/21 11:30 AM | 12/3/21 11:30 AM | SV Darmstadt 98 | Fortuna Düsseldorf | 1-3 | 2 - 4 points |
| 12/4/21 6:30 AM | 12/4/21 6:30 AM | 1. FC Nürnberg | Holstein Kiel | 2-1 | 2 - 4 points |
| 12/4/21 6:30 AM | 12/4/21 6:30 AM | SV Sandhausen | SC Paderborn 07 | 1-1 | 2 - 4 points |
| 12/4/21 6:30 AM | 12/4/21 6:30 AM | FC Hansa Rostock | FC Ingolstadt | 1-1 | 2 - 4 points |
| 12/4/21 1:30 PM | 12/4/21 1:30 PM | FC St. Pauli | FC Schalke 04 | 2-1 | 2 - 4 points |
| 12/5/21 6:30 AM | 12/5/21 6:30 AM | Hannover 96 | Hamburger SV | 1-0 | 2 - 4 points |
| 12/5/21 6:30 AM | 12/5/21 6:30 AM | Dynamo Dresden | Karlsruher SC | 3-1 | 2 - 4 points |
| 12/5/21 6:30 AM | 12/5/21 6:30 AM | 1. FC Heidenheim 1846 | Jahn Regensburg | 3-0 | 2 - 4 points |