Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 11/26/21 11:30 AM | 11/26/21 11:30 AM | Jahn Regensburg | Dynamo Dresden | 3-1 | 2 - 4 points |
| 11/26/21 11:30 AM | 11/26/21 11:30 AM | Fortuna Düsseldorf | 1. FC Heidenheim 1846 | 0-1 | 2 - 4 points |
| 11/27/21 6:30 AM | 11/27/21 6:30 AM | Karlsruher SC | Hannover 96 | 4-0 | 2 - 4 points |
| 11/27/21 6:30 AM | 11/27/21 6:30 AM | Erzgebirge Aue | SV Darmstadt 98 | 1-2 | 2 - 4 points |
| 11/27/21 6:30 AM | 11/27/21 6:30 AM | FC Schalke 04 | SV Sandhausen | 5-2 | 2 - 4 points |
| 11/27/21 1:30 PM | 11/27/21 1:30 PM | Holstein Kiel | Werder Bremen | 2-1 | 2 - 4 points |
| 11/28/21 6:30 AM | 11/28/21 6:30 AM | SC Paderborn 07 | FC Hansa Rostock | 1-1 | 2 - 4 points |
| 11/28/21 6:30 AM | 11/28/21 6:30 AM | 1. FC Nürnberg | FC St. Pauli | 2-3 | 2 - 4 points |
| 11/28/21 6:30 AM | 11/28/21 6:30 AM | Hamburger SV | FC Ingolstadt | 3-0 | 2 - 4 points |