Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 11/5/21 12:30 PM | 11/5/21 12:30 PM | Holstein Kiel | Dynamo Dresden | 2-1 | 2 - 4 points |
| 11/5/21 12:30 PM | 11/5/21 12:30 PM | 1. FC Nürnberg | Werder Bremen | 1-2 | 2 - 4 points |
| 11/6/21 7:30 AM | 11/6/21 7:30 AM | Fortuna Düsseldorf | Hannover 96 | 1-1 | 2 - 4 points |
| 11/6/21 7:30 AM | 11/6/21 7:30 AM | SC Paderborn 07 | FC Ingolstadt | 2-1 | 2 - 4 points |
| 11/6/21 7:30 AM | 11/6/21 7:30 AM | Jahn Regensburg | FC Hansa Rostock | 2-3 | 2 - 4 points |
| 11/6/21 2:30 PM | 11/6/21 2:30 PM | Karlsruher SC | Hamburger SV | 1-1 | 2 - 4 points |
| 11/7/21 6:30 AM | 11/7/21 6:30 AM | Erzgebirge Aue | 1. FC Heidenheim 1846 | 2-0 | 2 - 4 points |
| 11/7/21 6:30 AM | 11/7/21 6:30 AM | FC Schalke 04 | SV Darmstadt 98 | 2-4 | 2 - 4 points |
| 11/24/21 11:30 AM | 11/24/21 11:30 AM | FC St. Pauli | SV Sandhausen | 3-1 | 2 - 4 points |