Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 1/14/22 11:30 AM | 1/14/22 11:30 AM | FC Hansa Rostock | Hannover 96 | 0-1 | 2 - 4 points |
| 1/14/22 11:30 AM | 1/14/22 11:30 AM | Dynamo Dresden | Hamburger SV | 1-1 | 2 - 4 points |
| 1/15/22 6:30 AM | 1/15/22 6:30 AM | Werder Bremen | Fortuna Düsseldorf | 3-0 | 2 - 4 points |
| 1/15/22 6:30 AM | 1/15/22 6:30 AM | FC St. Pauli | Erzgebirge Aue | 2-2 | 2 - 4 points |
| 1/15/22 6:30 AM | 1/15/22 6:30 AM | 1. FC Nürnberg | SC Paderborn 07 | 1-2 | 2 - 4 points |
| 1/15/22 1:30 PM | 1/15/22 1:30 PM | SV Darmstadt 98 | Karlsruher SC | 2-2 | 2 - 4 points |
| 1/16/22 6:30 AM | 1/16/22 6:30 AM | FC Schalke 04 | Holstein Kiel | 1-1 | 2 - 4 points |
| 1/16/22 6:30 AM | 1/16/22 6:30 AM | 1. FC Heidenheim 1846 | FC Ingolstadt | 2-1 | 2 - 4 points |
| 1/16/22 6:30 AM | 1/16/22 6:30 AM | SV Sandhausen | Jahn Regensburg | 0-3 | 2 - 4 points |