| Date | Dead line | Home | Away | Result | Points rule |
|---|
| 4/22/22 1:30 PM | 4/22/22 1:00 PM | VfL Wolfsburg | FSV Mainz 05 | 5-0 | 2 - 4 points |
| 4/23/22 8:30 AM | 4/23/22 8:00 AM | RB Leipzig | 1. FC Union Berlin | 1-2 | 2 - 4 points |
| 4/23/22 8:30 AM | 4/23/22 8:00 AM | SpVgg Greuther Fürth | Bayer 04 Leverkusen | 1-4 | 2 - 4 points |
| 4/23/22 8:30 AM | 4/23/22 8:00 AM | 1. FC Köln | Arminia Bielefeld | 3-1 | 2 - 4 points |
| 4/23/22 8:30 AM | 4/23/22 8:00 AM | SC Freiburg | Bor. Mönchengladbach | 3-3 | 2 - 4 points |
| 4/23/22 8:30 AM | 4/23/22 8:00 AM | Eintracht Frankfurt | 1899 Hoffenheim | 2-2 | 2 - 4 points |
| 4/23/22 11:30 AM | 4/23/22 11:00 AM | FC Bayern Munich | Borussia Dortmund | 3-1 | 2 - 4 points |
| 4/24/22 8:30 AM | 4/24/22 8:00 AM | VfL Bochum | FC Augsburg | 0-2 | 2 - 4 points |
| 4/24/22 10:30 AM | 4/24/22 10:00 AM | Hertha BSC | VfB Stuttgart | 2-0 | 2 - 4 points |
