Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 9/24/21 1:00 PM | 9/24/21 1:00 PM | Sporting Lisbon | Maritimo Funchal | 1-0 | 5 - 7 points |
| 9/24/21 3:15 PM | 9/24/21 3:15 PM | FC Gil Vicente | FC Porto | 1-2 | 5 - 7 points |
| 9/25/21 9:30 AM | 9/25/21 9:30 AM | Moreirense FC | FC Arouca | 2-1 | 5 - 7 points |
| 9/25/21 12:00 PM | 9/25/21 12:00 PM | Vitoria Guimaraes | Benfica Lisbon | 1-3 | 5 - 7 points |
| 9/25/21 2:30 PM | 9/25/21 2:30 PM | CD Tondela | FC Famalicao | 3-2 | 5 - 7 points |
| 9/26/21 12:00 PM | 9/26/21 12:00 PM | Santa Clara | Sporting Braga | 1-1 | 5 - 7 points |
| 9/26/21 2:30 PM | 9/26/21 2:30 PM | Portimonense | FC Vizela | 0-0 | 5 - 7 points |
| 9/27/21 1:00 PM | 9/27/21 1:00 PM | FC Pacos de Ferreira | Belenenses Lisbon | 2-2 | 5 - 7 points |
| 9/27/21 3:15 PM | 9/27/21 3:15 PM | Boavista Porto | Estoril Praia | 1-1 | 5 - 7 points |