Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 9/17/21 2:15 PM | 9/17/21 2:15 PM | Portimonense | Santa Clara | 2-1 | 5 - 7 points |
| 9/18/21 9:30 AM | 9/18/21 9:30 AM | FC Famalicao | Maritimo Funchal | 0-0 | 5 - 7 points |
| 9/18/21 12:00 PM | 9/18/21 12:00 PM | Belenenses Lisbon | FC Gil Vicente | 1-1 | 5 - 7 points |
| 9/18/21 2:30 PM | 9/18/21 2:30 PM | FC Arouca | Vitoria Guimaraes | 2-2 | 5 - 7 points |
| 9/19/21 9:30 AM | 9/19/21 9:30 AM | FC Vizela | FC Pacos de Ferreira | 1-1 | 5 - 7 points |
| 9/19/21 12:00 PM | 9/19/21 12:00 PM | FC Porto | Moreirense FC | 5-0 | 5 - 7 points |
| 9/19/21 2:30 PM | 9/19/21 2:30 PM | Estoril Praia | Sporting Lisbon | 0-1 | 5 - 7 points |
| 9/20/21 1:00 PM | 9/20/21 1:00 PM | Benfica Lisbon | Boavista Porto | 3-1 | 5 - 7 points |
| 9/20/21 3:15 PM | 9/20/21 3:15 PM | Sporting Braga | CD Tondela | 3-1 | 5 - 7 points |