Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 9/11/21 9:30 AM | 9/11/21 9:30 AM | FC Pacos de Ferreira | Sporting Braga | 0-0 | 5 - 7 points |
| 9/11/21 12:00 PM | 9/11/21 12:00 PM | Santa Clara | Benfica Lisbon | 0-5 | 5 - 7 points |
| 9/11/21 2:30 PM | 9/11/21 2:30 PM | Sporting Lisbon | FC Porto | 1-1 | 5 - 7 points |
| 9/12/21 9:30 AM | 9/12/21 9:30 AM | Moreirense FC | FC Famalicao | 2-2 | 5 - 7 points |
| 9/12/21 12:00 PM | 9/12/21 12:00 PM | FC Gil Vicente | FC Vizela | 2-2 | 5 - 7 points |
| 9/12/21 12:00 PM | 9/12/21 12:00 PM | Boavista Porto | Portimonense | 1-1 | 5 - 7 points |
| 9/12/21 2:30 PM | 9/12/21 2:30 PM | Vitoria Guimaraes | Belenenses Lisbon | 0-0 | 5 - 7 points |
| 9/13/21 1:00 PM | 9/13/21 1:00 PM | Maritimo Funchal | FC Arouca | 2-2 | 5 - 7 points |
| 9/13/21 3:15 PM | 9/13/21 3:15 PM | CD Tondela | Estoril Praia | 1-2 | 5 - 7 points |