Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 4/8/22 2:15 PM | 4/8/22 2:15 PM | FC Gil Vicente | Moreirense FC | 1-2 | 5 - 7 points |
| 4/9/22 9:30 AM | 4/9/22 9:30 AM | FC Pacos de Ferreira | Maritimo Funchal | 2-0 | 5 - 7 points |
| 4/9/22 12:00 PM | 4/9/22 12:00 PM | Boavista Porto | FC Arouca | 1-0 | 5 - 7 points |
| 4/9/22 12:00 PM | 4/9/22 12:00 PM | Benfica Lisbon | Belenenses Lisbon | 3-1 | 5 - 7 points |
| 4/9/22 2:30 PM | 4/9/22 2:30 PM | CD Tondela | Sporting Lisbon | 1-3 | 5 - 7 points |
| 4/10/22 9:30 AM | 4/10/22 9:30 AM | Santa Clara | Estoril Praia | 2-0 | 5 - 7 points |
| 4/10/22 9:30 AM | 4/10/22 9:30 AM | Portimonense | FC Famalicao | 1-0 | 5 - 7 points |
| 4/10/22 12:00 PM | 4/10/22 12:00 PM | Vitoria Guimaraes | FC Porto | 0-1 | 5 - 7 points |
| 4/10/22 2:30 PM | 4/10/22 2:30 PM | FC Vizela | Sporting Braga | 0-1 | 5 - 7 points |