Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 12/10/21 2:15 PM | 12/10/21 2:15 PM | FC Pacos de Ferreira | FC Gil Vicente | 0-1 | 5 - 7 points |
| 12/11/21 9:30 AM | 12/11/21 9:30 AM | Maritimo Funchal | Santa Clara | 4-1 | 5 - 7 points |
| 12/11/21 12:00 PM | 12/11/21 12:00 PM | Vitoria Guimaraes | CD Tondela | 5-2 | 5 - 7 points |
| 12/11/21 2:30 PM | 12/11/21 2:30 PM | Sporting Lisbon | Boavista Porto | 2-0 | 5 - 7 points |
| 12/12/21 9:30 AM | 12/12/21 9:30 AM | Moreirense FC | Portimonense | 0-1 | 5 - 7 points |
| 12/12/21 9:30 AM | 12/12/21 9:30 AM | Belenenses Lisbon | Estoril Praia | 0-1 | 5 - 7 points |
| 12/12/21 12:00 PM | 12/12/21 12:00 PM | FC Famalicao | Benfica Lisbon | 1-4 | 5 - 7 points |
| 12/12/21 2:30 PM | 12/12/21 2:30 PM | FC Porto | Sporting Braga | 1-0 | 5 - 7 points |
| 12/13/21 2:15 PM | 12/13/21 2:15 PM | FC Arouca | FC Vizela | 1-4 | 5 - 7 points |