Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 2/25/22 1:00 PM | 2/25/22 1:00 PM | RKC Waalwijk | FC Twente Enschede | 1-2 | 5 - 7 points |
| 2/26/22 9:30 AM | 2/26/22 9:30 AM | Heracles Almelo | PEC Zwolle | 2-0 | 5 - 7 points |
| 2/26/22 11:45 AM | 2/26/22 11:45 AM | FC Groningen | Willem II Tilburg | 1-0 | 5 - 7 points |
| 2/26/22 2:00 PM | 2/26/22 2:00 PM | Cambuur-Leeuwarden | Fortuna Sittard | 2-1 | 5 - 7 points |
| 2/27/22 5:15 AM | 2/27/22 5:15 AM | AZ Alkmaar | Feyenoord Rotterdam | 2-1 | 5 - 7 points |
| 2/27/22 5:15 AM | 2/27/22 5:15 AM | Vitesse Arnheim | NEC Nijmwegen | 4-1 | 5 - 7 points |
| 2/27/22 7:35 AM | 2/27/22 7:35 AM | Sparta Rotterdam | PSV Eindhoven | 1-2 | 5 - 7 points |
| 2/27/22 9:45 AM | 2/27/22 9:45 AM | Go Ahead Eagles Deventer | Ajax Amsterdam | 2-1 | 5 - 7 points |
| 2/27/22 1:00 PM | 2/27/22 1:00 PM | SC Heerenveen | FC Utrecht | 1-2 | 5 - 7 points |