| Date | Home | Away | Result |
|---|---|---|---|
| 9/12/25 1:30 PM | Bayer 04 Leverkusen | Eintracht Frankfurt | 3-1 |
| 9/13/25 8:30 AM | 1. FC Union Berlin | 1899 Hoffenheim | 2-4 |
| 9/13/25 8:30 AM | VfL Wolfsburg | 1. FC Köln | 3-3 |
| 9/13/25 8:30 AM | 1. FC Heidenheim 1846 | Borussia Dortmund | 0-2 |
| 9/13/25 8:30 AM | SC Freiburg | VfB Stuttgart | 3-1 |
| 9/13/25 8:30 AM | FSV Mainz 05 | RB Leipzig | 0-1 |
| 9/13/25 11:30 AM | FC Bayern Munich | Hamburger SV | 5-0 |
| 9/14/25 8:30 AM | FC St. Pauli | FC Augsburg | 2-1 |
| 9/14/25 10:30 AM | Bor. Mönchengladbach | Werder Bremen | 0-4 |