Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 4/9/22 7:00 AM | 4/9/22 7:00 AM | Alessandria Calcio | Pordenone | 2-0 | 5 - 7 points |
| 4/9/22 7:00 AM | 4/9/22 7:00 AM | Como Calcio | AS Cittadella | 1-2 | 5 - 7 points |
| 4/9/22 7:00 AM | 4/9/22 7:00 AM | US Lecce | SPAL Ferrara | 1-0 | 5 - 7 points |
| 4/9/22 9:15 AM | 4/9/22 9:15 AM | Frosinone Calcio | US Cremonese | 2-1 | 5 - 7 points |
| 4/10/22 7:30 AM | 4/10/22 7:30 AM | Benevento Calcio | Vicenza Calcio | 1-0 | 5 - 7 points |
| 4/10/22 8:30 AM | 4/10/22 8:30 AM | Ascoli Calcio | Reggina 1914 | 2-0 | 5 - 7 points |
| 4/10/22 8:30 AM | 4/10/22 8:30 AM | FC Crotone | Ternana Calcio | 1-2 | 5 - 7 points |
| 4/10/22 8:30 AM | 4/10/22 8:30 AM | Cosenza Calcio | AC Monza | 0-2 | 5 - 7 points |
| 4/10/22 11:00 AM | 4/10/22 11:00 AM | AC Perugia | Pisa Sporting Club | 1-1 | 5 - 7 points |
| 4/11/22 1:30 PM | 4/11/22 1:30 PM | Brescia Calcio | Parma Calcio 1913 | 1-0 | 5 - 7 points |